Advanced Organic Chemistry: C13 NMR spectrum of propan-2-amine C3H9N (CH3)2CHNH2

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Interpreting and explaining the Carbon-13 NMR spectrum of propan-2-amine (2-aminopropane, 2-propanamine, 2-propylamine, isopropylamine)

[Author © Dr Phil Brown PhD: Doc Brown's advanced level organic chemistry exam revision notes suitable for students of UK A level chemistry courses & US K12 grade 11, grade 12 and AP honors chemistry courses: Molecular spectroscopy - analysing the 13C NMR spectra of propan-2-amine (isopropylamine) [spectra page updated April 4th 2026 *]

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Introductory note on the 13C NMR spectrum of propan-2-amine

Students and teachers please note that my explanation of the carbon-13 NMR spectrum of propan-2-amine is designed for advanced, but pre-university, chemistry courses.

The description does not involve the chemical shift δ spin-spin coupling effects for propan-2-amine and the relative size of the carbon-13 NMR shifts does not give the ratio of the carbon atoms in the different non-equivalent chemical environments of the propan-2-amine molecule.

The most common solvent used for investigating the 13C NMR spectrum of compounds like propan-2-amine, is CDCl3 and other deuterated solvents.

13C nmr spectrum of propan-2-amine (2-aminopropane) C3H9N (CH3)2CHNH2 analysis of chemical shifts ppm interpretation of C-13 chemical shifts ppm of isopropylamine 2-propylamine 2-propanamine C13 13-C nmr doc brown's advanced organic chemistry revision notes 

TMS is the acronym for tetramethylsilane, formula Si(CH3)4, whose 13C atoms are arbitrarily given a chemical shift of 0.0 ppm. This is the 'standard' in 13C NMR spectroscopy and all other 13C resonances, called chemical shifts, are measured with respect to the TMS, and depend on the individual (electronic) chemical environment of the 13C atoms in an organic molecule - propan-2-amine (2-aminopropane) here.

propan-2-amine, 2-aminopropane, 2-propylamine, 2-propanamine, isopropylamine, (c) doc b

 (c) doc b The classification, structure and naming of organic nitrogen compounds

Interpreting the C-13 NMR spectrum of propan-2-amine (2-aminopropane)

As you can see from the diagram above there are 2 different 13C chemical shift lines in the C-13 NMR spectrum of propan-2-amine (2-aminopropane) indicating 2 different chemical environments of the 3 carbon atoms of propan-2-amine (2-aminopropane).

(CH3)2CHNH2

(Note the 2 different colours indicating the 2 different chemical environments of the 3 carbon atoms in propan-2-amine (2-aminopropane)).

13C chemical shifts (a) to (b) on the C-13 NMR spectrum diagram for propan-2-amine (2-aminopropane).

The two carbon atoms of the methyl groups are equivalent to each other.

The carbon-13 NMR spectra provides direct evidence of 2 different carbon atom environments for the 3 carbon atoms in the propan-2-amine (2-aminopropane) molecule, deduced from the presence of 3 different 13C NMR chemical shifts (ppm).


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Links associated with propan-2-amine (2-aminopropane)

The infrared spectra of propan-2-amine (2-aminopropane, 2-propylamine, isopropylamine)

The mass spectra of propan-2-amine (2-aminopropane, 2-propylamine, isopropylamine)

The H-1 NMR spectra of propan-2-amine (2-aminopropane, 2-propylamine, isopropylamine)

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